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Prevalence of Anxiety, Depression and Attention Deficit Disorder (ADD) in Patients with Primary Hyperhidrosis
Introduction: Primary hyperhidrosis (HH) is a socially disabling disorder with a significant impact on quality of life. Few studies have attempted to estimate the prevalence of mental illness in patients with hyperhidrosis, and the results have been conflicting. We seek to further understand the correlation between depression, anxiety and ADD with hyperhidrosis location and severity

Methods: Patients diagnosed with primary hyperhidrosis from 2011-2018 at a single site were identified. Age of onset, age at time of initial evaluation, gender, hyperhidrosis location and Hyperhidrosis Disease Severity Scale (HDSS) were recorded. HDSS was used as a maker of location severity. Patients were considered to have anxiety, depression, or ADHD if patient self reported the diagnosis in the intake form, had an ICD9 code, a clinical note documenting diagnosis or if taking ADD specific medication.

Results: 500 patients were included. 13.8% of patients had a diagnosis of anxiety, 12.4% had depression and 6.4% had ADD, which is significantly higher than the general population. There were positive correlations between the number of anatomical HH sites involved and the prevalence of psychiatric conditions. However, there was no association with overall HDSS severity or location involved with prevalence of psychiatric conditions.

Conclusion: There is a significant association between HH and the prevalence of anxiety, depression and ADD regardless of gender or age. Compared to the nationally reported prevalence of anxiety, depression and ADD, HH patients have a statistically significant higher prevalence than the general public. The severity and/or location of HH do not correlate with prevalence of anxiety, depression and ADD but the number of anatomical sites involved does. Providers should be aware of the increased prevalence of mental health disorders in patients with hyperhidrosis.
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