C001 - Structure and Function of the Skin: Development, Cell Biology, and Skin Structure
Friday, March 1; 9:00 AM - 12:00 PM
Following this course, the attendee should be able to:
- Describe the embryonic origin, patterning, and differentiation of cells that contribute to the skin
- Describe the cells of the epidermis, dermis, and subcutis, and define their functions
- Define skin diseases occurring from genetic or immunologic dysfunction of cell adhesion and extracellular matrix components
This session will discuss the development and normal functions of the skin with an emphasis on describing specific cell components involved in the pathophysiology of skin diseases. Focus will be on skin embryology, differentiation and patterning; functions of keratinocytes; cells of the dermis; epidermal cell-cell and cell-matrix adhesion structures; and the extracellular matrix. Examples will be shown of how knowledge of skin biology is essential to interpreting clinical presentations and design of patient care. The curriculum is a basic overview of skin biology for residents and dermatologists.
- Di Nardo, Anna, MD, PhD: no financial relationships exist with commercial interests.
- Lee, Carolyn S., MD, PhD: no financial relationships exist with commercial interests.
- Sun, Bryan, MD, PhD: no financial relationships exist with commercial interests.
- Uitto, Jouni J., MD, PhD: no financial relationships exist with commercial interests.
- Yancey, Kim B., MD: Genentech, Inc. – C(H); UpToDate, Inc – O(H);
Dr. Sun / Introduction
Dr. Sun / Skin Embryology and Development
Dr. Lee / Structure and Function of the Epidermis
Dr. Di Nardo / Structure and Function of the Dermis
Dr. Uitto / Extracellular Matrix and Associated Diseases
Dr. Yancey / Immunobullous Skin Diseases